Exercise 3

Logo Avogadro

If you have not already done so, download Avogadro for free and watch the tutorials if necessary.

Encephalins are brain peptides with opiate activity. An encephalin molecule is described by Try-Gly-Gly-Phe-Leu amino acid sequence.

Open Avogadro and then build the encephaline molecule by writing the sequence given (sequence BuildInsert Peptide).

After optimizing and rotating the structure properly, open a new page of Avogadro and import the leucine molecule. Compare the two molecules: can you identify the position of the leucine in the encephalin?

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